The nonthiazolidinedione PPARgamma agonist L-796,449 is neuroprotective in experimental stroke. [electronic resource]
- Journal of neuropathology and experimental neurology Sep 2005
- 797-805 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3069
10.1097/01.jnen.0000178852.83680.3c doi
Animals Benzofurans--therapeutic use Blotting, Western Brain Ischemia--drug therapy Caspase 3 Caspases--metabolism Cyclooxygenase 2 Disease Models, Animal Electrophoretic Mobility Shift Assay Heme Oxygenase (Decyclizing)--biosynthesis Heme Oxygenase-1 I-kappa B Proteins--drug effects Inflammation--prevention & control Male Matrix Metalloproteinase 9--biosynthesis NF-kappa B--drug effects Neuroprotective Agents--therapeutic use Nitric Oxide Synthase--biosynthesis Nitric Oxide Synthase Type II PPAR gamma--agonists Phenylacetates--therapeutic use Prostaglandin-Endoperoxide Synthases--biosynthesis Rats