TY  - GEN
AU  - Rikitake,Yoshiyuki
AU  - Kim,Hyung-Hwan
AU  - Huang,Zhihong
AU  - Seto,Minoru
AU  - Yano,Kazuo
AU  - Asano,Toshio
AU  - Moskowitz,Michael A
AU  - Liao,James K
TI  - Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection
SN  - 1524-4628
PY  - 2006///0112
KW  - 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
KW  - analogs & derivatives
KW  - Amides
KW  - pharmacology
KW  - Analysis of Variance
KW  - Animals
KW  - Antihypertensive Agents
KW  - Aorta
KW  - cytology
KW  - Blotting, Northern
KW  - Blotting, Western
KW  - Brain Ischemia
KW  - pathology
KW  - Cattle
KW  - Cell Line
KW  - Cells, Cultured
KW  - Cerebrovascular Circulation
KW  - Dose-Response Relationship, Drug
KW  - Down-Regulation
KW  - Endothelium, Vascular
KW  - Enzyme Inhibitors
KW  - Humans
KW  - Hypoxia
KW  - Infarction, Middle Cerebral Artery
KW  - Intracellular Signaling Peptides and Proteins
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Neuroprotective Agents
KW  - Nitric Oxide
KW  - metabolism
KW  - Nitric Oxide Synthase
KW  - Nitric Oxide Synthase Type III
KW  - biosynthesis
KW  - Protein Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Pyridines
KW  - RNA, Messenger
KW  - Regional Blood Flow
KW  - Stroke
KW  - prevention & control
KW  - Time Factors
KW  - Umbilical Veins
KW  - Up-Regulation
KW  - rho-Associated Kinases
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1161/01.STR.0000181077.84981.11
ER  -