Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway. [electronic resource]
- The Journal of biological chemistry Oct 2005
- 35337-45 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M506460200 doi
Adaptor Proteins, Signal Transducing--chemistry Amino Acid Motifs Amino Acid Sequence Animals Apoptosis Aspartic Acid--chemistry Binding Sites Caspase 7 Caspases--chemistry Cell Cycle Cell Line Cell Nucleus--metabolism Cell-Free System Checkpoint Kinase 1 Cycloheximide--pharmacology Cytosol--metabolism DNA--chemistry DNA Replication Dose-Response Relationship, Drug Drosophila Etoposide--pharmacology HeLa Cells Humans Immunoprecipitation Jurkat Cells Mice Models, Biological Molecular Sequence Data Oligonucleotides--chemistry Phosphorylation Protein Binding Protein Kinases--metabolism Protein Structure, Tertiary Protein Synthesis Inhibitors--pharmacology Recombinant Proteins--chemistry Sequence Homology, Amino Acid Signal Transduction Time Factors Xenopus Xenopus Proteins