Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes. [electronic resource]
- Nature biotechnology Sep 2005
- 1171-6 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
1087-0156
10.1038/nbt1128 doi
Amino Acid Sequence Biotechnology--methods Combinatorial Chemistry Techniques Escherichia coli--metabolism Genetic Engineering--methods Lactones--chemistry Macrolides--chemistry Models, Chemical Molecular Sequence Data Plasmids--metabolism Polyketide Synthases--biosynthesis Protein Engineering--methods Protein Structure, Tertiary Sequence Homology, Amino Acid