TY  - GEN
AU  - Rahmani,Mohamed
AU  - Davis,Eric Maynard
AU  - Bauer,Cheryl
AU  - Dent,Paul
AU  - Grant,Steven
TI  - Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation
SN  - 0021-9258
PY  - 2005///1213
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - Benzenesulfonates
KW  - Caspase 3
KW  - Caspase 7
KW  - Caspase 9
KW  - Caspases
KW  - biosynthesis
KW  - Cell Line, Tumor
KW  - Chromatography
KW  - Dose-Response Relationship, Drug
KW  - Down-Regulation
KW  - Enzyme Inhibitors
KW  - Genes, Reporter
KW  - Humans
KW  - Immunoblotting
KW  - Immunoprecipitation
KW  - Jurkat Cells
KW  - K562 Cells
KW  - Leukemia
KW  - drug therapy
KW  - Myeloid Cell Leukemia Sequence 1 Protein
KW  - Neoplasm Proteins
KW  - Niacinamide
KW  - analogs & derivatives
KW  - Phenylurea Compounds
KW  - Phosphorylation
KW  - Promoter Regions, Genetic
KW  - Protein Biosynthesis
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Pyridines
KW  - RNA, Messenger
KW  - metabolism
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Sorafenib
KW  - Subcellular Fractions
KW  - Time Factors
KW  - Transcription, Genetic
KW  - Transfection
KW  - U937 Cells
KW  - Ubiquitin
KW  - chemistry
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.M506551200
ER  -