TY - GEN AU - Yang,Xinping AU - Liu,Liyun AU - Sternberg,David AU - Tang,Liren AU - Galinsky,Ilene AU - DeAngelo,Daniel AU - Stone,Richard TI - The FLT3 internal tandem duplication mutation prevents apoptosis in interleukin-3-deprived BaF3 cells due to protein kinase A and ribosomal S6 kinase 1-mediated BAD phosphorylation at serine 112 SN - 0008-5472 PY - 2005///1027 KW - Amino Acid Sequence KW - Animals KW - Apoptosis KW - drug effects KW - Butadienes KW - pharmacology KW - Carrier Proteins KW - metabolism KW - Cyclic AMP-Dependent Protein Kinases KW - antagonists & inhibitors KW - Drug Synergism KW - Enzyme Activation KW - Hematopoietic Stem Cells KW - cytology KW - Interleukin-3 KW - deficiency KW - Isoquinolines KW - MAP Kinase Signaling System KW - Mice KW - Molecular Sequence Data KW - Mutation KW - Nitriles KW - Phosphorylation KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - biosynthesis KW - RNA Interference KW - Receptor Protein-Tyrosine Kinases KW - Ribosomal Protein S6 Kinases, 90-kDa KW - Serine KW - Sulfonamides KW - Tandem Repeat Sequences KW - genetics KW - Tyrphostins KW - bcl-Associated Death Protein KW - bcl-X Protein KW - fms-Like Tyrosine Kinase 3 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1158/0008-5472.CAN-04-2263 ER -