Hurtado, Andres

Poly (D,L-lactic acid) macroporous guidance scaffolds seeded with Schwann cells genetically modified to secrete a bi-functional neurotrophin implanted in the completely transected adult rat thoracic spinal cord. [electronic resource] - Biomaterials Jan 2006 - 430-42 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0142-9612

10.1016/j.biomaterials.2005.07.014 doi


Animals
Axons--chemistry
Blood Vessels--physiology
Cell Enlargement--drug effects
Cell Survival--drug effects
Chondroitin Sulfates--metabolism
Culture Media, Conditioned--pharmacology
Female
Ganglia, Spinal--cytology
Glial Fibrillary Acidic Protein--analysis
Green Fluorescent Proteins--genetics
Guided Tissue Regeneration--methods
Hindlimb--drug effects
Implants, Experimental
Lactic Acid--chemistry
Neovascularization, Physiologic
Nerve Fibers, Myelinated--physiology
Nerve Growth Factors--genetics
Nerve Regeneration
Neurotrophin 3--genetics
Polyesters
Polymers--chemistry
Rats
Rats, Inbred F344
Schwann Cells--cytology
Spinal Cord--metabolism
Spinal Cord Injuries--pathology
Thoracic Vertebrae
Transfection