TY  - GEN
AU  - Brautigan,D L
AU  - Brown,M
AU  - Grindrod,S
AU  - Chinigo,G
AU  - Kruszewski,A
AU  - Lukasik,S M
AU  - Bushweller,J H
AU  - Horal,M
AU  - Keller,S
AU  - Tamura,S
AU  - Heimark,D B
AU  - Price,J
AU  - Larner,A N
AU  - Larner,J
TI  - Allosteric activation of protein phosphatase 2C by D-chiro-inositol-galactosamine, a putative mediator mimetic of insulin action
SN  - 0006-2960
PY  - 2005///1017
KW  - Amino Acid Substitution
KW  - genetics
KW  - Animals
KW  - Binding Sites
KW  - Blood Glucose
KW  - drug effects
KW  - Chelating Agents
KW  - administration & dosage
KW  - Diabetes Mellitus, Experimental
KW  - drug therapy
KW  - Dose-Response Relationship, Drug
KW  - Drug Synergism
KW  - Enzyme Activation
KW  - Galactosamine
KW  - Hydrogen Bonding
KW  - Inositol
KW  - Inositol Phosphates
KW  - Insulin
KW  - Male
KW  - Manganese
KW  - chemistry
KW  - Models, Molecular
KW  - Nitrophenols
KW  - Organophosphorus Compounds
KW  - Phosphoprotein Phosphatases
KW  - Point Mutation
KW  - Protein Binding
KW  - Protein Phosphatase 2C
KW  - Protein Structure, Tertiary
KW  - Rats
KW  - Rats, Sprague-Dawley
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1021/bi0508845
ER  -