TY - GEN AU - Wang,Jian AU - Ouyang,Weiming AU - Li,Jingxia AU - Wei,Lixin AU - Ma,Qian AU - Zhang,Zhuo AU - Tong,Qiangsong AU - He,Jie AU - Huang,Chuanshu TI - Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation SN - 0008-5472 PY - 2005///1004 KW - Animals KW - Benzothiazoles KW - Cell Line KW - Down-Regulation KW - Epidermis KW - enzymology KW - JNK Mitogen-Activated Protein Kinases KW - metabolism KW - MAP Kinase Signaling System KW - Mice KW - NF-kappa B KW - physiology KW - PTEN Phosphohydrolase KW - Phosphoric Monoester Hydrolases KW - biosynthesis KW - Phosphorylation KW - radiation effects KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - RNA, Small Interfering KW - genetics KW - Ribosomal Protein S6 Kinases, 70-kDa KW - Thiazoles KW - pharmacology KW - Toluene KW - analogs & derivatives KW - Transcription Factor AP-1 KW - Transfection KW - Tumor Suppressor Protein p53 KW - antagonists & inhibitors KW - Tumor Suppressor Proteins KW - Ultraviolet Rays KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1158/0008-5472.CAN-04-4184 ER -