TY  - GEN
AU  - Tachibana,Shuko
AU  - Fujimaki,Yuko
AU  - Yokoyama,Hiroyuki
AU  - Okazaki,Osamu
AU  - Sudo,Ken-ichi
TI  - In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions
SN  - 0090-9556
PY  - 2006///0804
KW  - Aryl Hydrocarbon Hydroxylases
KW  - antagonists & inhibitors
KW  - Calmodulin
KW  - Cytochrome P-450 CYP1A2
KW  - metabolism
KW  - Cytochrome P-450 CYP1A2 Inhibitors
KW  - Cytochrome P-450 CYP2C19
KW  - Cytochrome P-450 CYP2C8
KW  - Cytochrome P-450 CYP2C9
KW  - Cytochrome P-450 CYP2D6
KW  - Cytochrome P-450 CYP2D6 Inhibitors
KW  - Cytochrome P-450 CYP2E1
KW  - Cytochrome P-450 CYP2E1 Inhibitors
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - Cytochrome P-450 Enzyme System
KW  - Dose-Response Relationship, Drug
KW  - Drug Interactions
KW  - Humans
KW  - In Vitro Techniques
KW  - Indazoles
KW  - Kinetics
KW  - Microsomes, Liver
KW  - enzymology
KW  - Mixed Function Oxygenases
KW  - Recombinant Proteins
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1124/dmd.105.004903
ER  -