TY - GEN AU - Kohn,Jonathan E AU - Plaxco,Kevin W TI - Engineering a signal transduction mechanism for protein-based biosensors SN - 0027-8424 PY - 2005///0920 KW - Biosensing Techniques KW - methods KW - Humans KW - In Vitro Techniques KW - Kinetics KW - Ligands KW - Mutagenesis KW - Nuclear Magnetic Resonance, Biomolecular KW - Protein Conformation KW - Protein Engineering KW - Protein Folding KW - Proto-Oncogene Proteins KW - chemistry KW - Proto-Oncogene Proteins c-fyn KW - Recombinant Proteins KW - Sequence Deletion KW - Signal Transduction KW - src Homology Domains KW - src-Family Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1073/pnas.0503055102 ER -