Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necrosis factor family effector pathways. [electronic resource]
- Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Aug 2005
- 576-86 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
1083-8791
10.1016/j.bbmt.2005.05.006 doi
Animals Apoptosis Regulatory Proteins Bone Marrow Transplantation--immunology CD8-Positive T-Lymphocytes--immunology Carrier Proteins--immunology Cell Line Cytokine TWEAK Fas Ligand Protein Graft Survival--immunology Immunologic Memory--genetics Membrane Glycoproteins--immunology Membrane Proteins--immunology Mice Mice, Knockout Minor Histocompatibility Antigens--immunology Pore Forming Cytotoxic Proteins Signal Transduction--immunology Transplantation Immunology Transplantation, Homologous Tumor Necrosis Factors