Fandy, Tamer E <br/><br/>
Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.  [electronic resource] 

 -  Neoplasia (New York, N.Y.)  Jul 2005 
 - 646-57 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1522-8002 
<br/><br/><label>Standard No.: </label>10.1593/neo.04655  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Chloromethyl Ketones--pharmacology<br/>Annexin A5--pharmacology<br/>Apoptosis<br/>Apoptosis Regulatory Proteins<br/>Calpain--metabolism<br/>Caspases--metabolism<br/>Cell Cycle--drug effects<br/>Cell Cycle Proteins--metabolism<br/>Cell Line, Tumor<br/>Cell Proliferation<br/>Cyclin-Dependent Kinase Inhibitor p27<br/>DNA-Binding Proteins--metabolism<br/>Dose-Response Relationship, Drug<br/>Down-Regulation<br/>E2F Transcription Factors<br/>Enzyme Inhibitors--pharmacology<br/>Flow Cytometry<br/>G1 Phase<br/>Gene Expression Regulation, Neoplastic<br/>Histone Deacetylase Inhibitors<br/>Histones--metabolism<br/>Humans<br/>Immunoblotting<br/>Inhibitory Concentration 50<br/>Leupeptins--pharmacology<br/>Luciferases--metabolism<br/>Membrane Glycoproteins--metabolism<br/>Membrane Potentials<br/>Microscopy, Fluorescence<br/>Mitochondria--metabolism<br/>Multiple Myeloma--metabolism<br/>NF-kappa B--metabolism<br/>Phosphorylation<br/>Propidium--pharmacology<br/>Protein Binding<br/>Ribonucleases--metabolism<br/>Subcellular Fractions--metabolism<br/>TNF-Related Apoptosis-Inducing Ligand<br/>Time Factors<br/>Transcription Factors--metabolism<br/>Tumor Necrosis Factor-alpha--metabolism<br/>Tumor Suppressor Proteins--metabolism<br/>Up-Regulation