Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats. [electronic resource]
- The Journal of pharmacology and experimental therapeutics Nov 2005
- 609-15 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3565
10.1124/jpet.105.089409 doi
Analgesics Analgesics, Opioid--pharmacology Animals Anti-Inflammatory Agents--pharmacology Antibodies, Blocking--pharmacology Cytokines--physiology Dose-Response Relationship, Drug Eicosanoids--pharmacology Endothelin A Receptor Antagonists Endothelins Foot Hot Temperature Hyperalgesia--chemically induced Injections, Subcutaneous Interleukin-12--administration & dosage Male Morphine--pharmacology Pain--chemically induced Pain Measurement--drug effects Physical Stimulation Rats Rats, Wistar Receptor, Endothelin B--drug effects Sympathetic Nervous System--drug effects