Hill, Courtney E

The L84F and the I143V polymorphisms in the O6-methylguanine-DNA-methyltransferase (MGMT) gene increase human sensitivity to the genotoxic effects of the tobacco-specific nitrosamine carcinogen NNK. [electronic resource] - Pharmacogenetics and genomics Aug 2005 - 571-8 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1744-6872

10.1097/01.fpc.0000167332.38528.a5 doi


Adult
Carcinogens--toxicity
Female
Humans
Male
Middle Aged
Mutagens--toxicity
Nitrosamines--toxicity
O(6)-Methylguanine-DNA Methyltransferase--genetics
Polymorphism, Genetic
Smoking
Tobacco Products