Brunkan, A L <br/><br/>
Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and gamma-secretase activity.  [electronic resource] 

 -  Journal of neurochemistry  Sep 2005 
 - 1315-28 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0022-3042 
<br/><br/><label>Standard No.: </label>10.1111/j.1471-4159.2005.03278.x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Amyloid Precursor Protein Secretases<br/>Animals<br/>Aspartic Acid Endopeptidases--metabolism<br/>Cells, Cultured<br/>Drug Stability<br/>Endopeptidases<br/>Endoplasmic Reticulum--metabolism<br/>Fibroblasts--enzymology<br/>Homeostasis--physiology<br/>Humans<br/>Membrane Glycoproteins--metabolism<br/>Membrane Proteins--genetics<br/>Mice<br/>Mice, Knockout<br/>Molecular Sequence Data<br/>Mutagenesis, Site-Directed<br/>Presenilin-1<br/>Protein Structure, Tertiary--physiology