TY - GEN AU - Dombrauckas,Jill D AU - Santarsiero,Bernard D AU - Mesecar,Andrew D TI - Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis SN - 0006-2960 PY - 2005///0915 KW - Allosteric Regulation KW - Allosteric Site KW - Animals KW - Catalysis KW - Crystallography, X-Ray KW - Enzyme Reactivators KW - chemistry KW - Enzyme Stability KW - Fructosediphosphates KW - Humans KW - Kinetics KW - Ligands KW - Models, Molecular KW - Neoplasm Proteins KW - antagonists & inhibitors KW - Oxalic Acid KW - Protein Conformation KW - Protein Structure, Tertiary KW - Pyruvate Kinase KW - Rabbits KW - Saccharomyces cerevisiae Proteins KW - Substrate Specificity KW - Thermodynamics N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1021/bi0474923 ER -