Nagano, Isao <br/><br/>
Therapeutic benefit of intrathecal injection of insulin-like growth factor-1 in a mouse model of Amyotrophic Lateral Sclerosis.  [electronic resource] 

 -  Journal of the neurological sciences  Aug 2005 
 - 61-8 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-510X 
<br/><br/><label>Standard No.: </label>10.1016/j.jns.2005.04.011  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Age Factors<br/>Amyotrophic Lateral Sclerosis--drug therapy<br/>Animals<br/>Blotting, Western--methods<br/>Cell Count--methods<br/>Disability Evaluation<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Extracellular Signal-Regulated MAP Kinases--metabolism<br/>Immunohistochemistry--methods<br/>Injections, Spinal--methods<br/>Insulin-Like Growth Factor I--therapeutic use<br/>Mice<br/>Mice, Transgenic<br/>Motor Neurons--drug effects<br/>Protein Serine-Threonine Kinases--metabolism<br/>Proto-Oncogene Proteins--metabolism<br/>Proto-Oncogene Proteins c-akt<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Superoxide Dismutase--genetics