Brouwer, Connie

Role of 5'-nucleotidase in thiopurine metabolism: enzyme kinetic profile and association with thio-GMP levels in patients with acute lymphoblastic leukemia during 6-mercaptopurine treatment. [electronic resource] - Clinica chimica acta; international journal of clinical chemistry Nov 2005 - 95-103 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0009-8981

10.1016/j.cccn.2005.05.006 doi


5'-Nucleotidase--metabolism
Child
Chromatography, High Pressure Liquid
Guanosine Monophosphate--blood
Humans
Hydrogen-Ion Concentration
Kinetics
Mercaptopurine--pharmacology
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Substrate Specificity
Sulfhydryl Compounds--chemistry
Thioguanine--metabolism