Nikolopoulos, Sotiris N

Targeted deletion of the integrin beta4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-kappaB, causing defects in epidermal growth and migration. [electronic resource] - Molecular and cellular biology Jul 2005 - 6090-102 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

0270-7306

10.1128/MCB.25.14.6090-6102.2005 doi


Active Transport, Cell Nucleus
Animals
Apoptosis
Cell Adhesion
Cell Adhesion Molecules--antagonists & inhibitors
Cell Movement
Cell Nucleus--metabolism
Epidermal Cells
Epidermal Growth Factor--pharmacology
Epidermis--growth & development
Gene Deletion
Gene Targeting
Integrin alpha6beta4--genetics
Integrin beta4--genetics
JNK Mitogen-Activated Protein Kinases--metabolism
Keratinocytes--drug effects
Mice
Mice, Mutant Strains
NF-kappa B--metabolism
Protein Structure, Tertiary
Signal Transduction
Wound Healing--genetics
Kalinin