Sun, Faneng

Dieldrin induces ubiquitin-proteasome dysfunction in alpha-synuclein overexpressing dopaminergic neuronal cells and enhances susceptibility to apoptotic cell death. [electronic resource] - The Journal of pharmacology and experimental therapeutics Oct 2005 - 69-79 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

0022-3565

10.1124/jpet.105.084632 doi


Animals
Apoptosis--drug effects
Caspase 3
Caspases--metabolism
Cell Line
DNA Fragmentation--drug effects
Dieldrin--toxicity
Dopamine--physiology
Dose-Response Relationship, Drug
Insecticides--toxicity
Neurons--drug effects
Oxidative Stress
Parkinsonian Disorders--chemically induced
Phagosomes--drug effects
Proteasome Endopeptidase Complex--physiology
Rats
Ubiquitin--metabolism