TY  - GEN
AU  - Shi,Guo Q
AU  - Dropinski,James F
AU  - McKeever,Brian M
AU  - Xu,Shihua
AU  - Becker,Joseph W
AU  - Berger,Joel P
AU  - MacNaul,Karen L
AU  - Elbrecht,Alex
AU  - Zhou,Gaochao
AU  - Doebber,Thomas W
AU  - Wang,Peiran
AU  - Chao,Yu-Sheng
AU  - Forrest,Mike
AU  - Heck,James V
AU  - Moller,David E
AU  - Jones,A Brian
TI  - Design and synthesis of alpha-aryloxyphenylacetic acid derivatives: a novel class of PPARalpha/gamma dual agonists with potent antihyperglycemic and lipid modulating activity
SN  - 0022-2623
PY  - 2005///0823
KW  - Animals
KW  - Cricetinae
KW  - Crystallography, X-Ray
KW  - Diabetes Mellitus, Type 2
KW  - drug therapy
KW  - Dogs
KW  - Hypoglycemic Agents
KW  - chemical synthesis
KW  - Hypolipidemic Agents
KW  - Kinetics
KW  - Male
KW  - Mesocricetus
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Models, Animal
KW  - Models, Molecular
KW  - Molecular Structure
KW  - PPAR alpha
KW  - agonists
KW  - PPAR delta
KW  - Phenylacetates
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm0502135
ER  -