TY  - GEN
AU  - Hardcastle,Anthea
AU  - Boxall,Kathy
AU  - Richards,Juliet
AU  - Tomlin,Peter
AU  - Sharp,Swee
AU  - Clarke,Paul
AU  - Workman,Paul
AU  - Aherne,Wynne
TI  - Solid-phase immunoassays in mechanism-based drug discovery: their application in the development of inhibitors of the molecular chaperone heat-shock protein 90
SN  - 1540-658X
PY  - 2006///0818
KW  - Animals
KW  - Benzoquinones
KW  - Blotting, Western
KW  - Carrier Proteins
KW  - antagonists & inhibitors
KW  - Cell Extracts
KW  - analysis
KW  - Dose-Response Relationship, Drug
KW  - Drug Design
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - HCT116 Cells
KW  - HSP70 Heat-Shock Proteins
KW  - HSP90 Heat-Shock Proteins
KW  - HT29 Cells
KW  - Heterocyclic Compounds, 2-Ring
KW  - Humans
KW  - Immunoassay
KW  - methods
KW  - Intracellular Signaling Peptides and Proteins
KW  - Lactams, Macrocyclic
KW  - Lymphocytes
KW  - chemistry
KW  - Mice
KW  - Neoplasm Transplantation
KW  - Proto-Oncogene Proteins c-raf
KW  - Pyrazoles
KW  - Quinones
KW  - Rifabutin
KW  - analogs & derivatives
KW  - Technology, Pharmaceutical
KW  - Transplantation, Heterologous
KW  - eIF-2 Kinase
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1089/adt.2005.3.273
ER  -