Hardcastle, Anthea <br/><br/>
Solid-phase immunoassays in mechanism-based drug discovery: their application in the development of inhibitors of the molecular chaperone heat-shock protein 90.  [electronic resource] 

 -  Assay and drug development technologies  Jun 2005 
 - 273-85 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1540-658X 
<br/><br/><label>Standard No.: </label>10.1089/adt.2005.3.273  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Benzoquinones<br/>Blotting, Western<br/>Carrier Proteins--antagonists & inhibitors<br/>Cell Extracts--analysis<br/>Dose-Response Relationship, Drug<br/>Drug Design<br/>Enzyme Inhibitors--pharmacology<br/>HCT116 Cells<br/>HSP70 Heat-Shock Proteins--antagonists & inhibitors<br/>HSP90 Heat-Shock Proteins--antagonists & inhibitors<br/>HT29 Cells<br/>Heterocyclic Compounds, 2-Ring--pharmacology<br/>Humans<br/>Immunoassay--methods<br/>Intracellular Signaling Peptides and Proteins<br/>Lactams, Macrocyclic<br/>Lymphocytes--chemistry<br/>Mice<br/>Neoplasm Transplantation<br/>Proto-Oncogene Proteins c-raf--antagonists & inhibitors<br/>Pyrazoles--pharmacology<br/>Quinones--pharmacology<br/>Rifabutin--analogs & derivatives<br/>Technology, Pharmaceutical--methods<br/>Transplantation, Heterologous<br/>eIF-2 Kinase--antagonists & inhibitors