TY  - GEN
AU  - Samuels,Yardena
AU  - Diaz,Luis A
AU  - Schmidt-Kittler,Oleg
AU  - Cummins,Jordan M
AU  - Delong,Laura
AU  - Cheong,Ian
AU  - Rago,Carlo
AU  - Huso,David L
AU  - Lengauer,Christoph
AU  - Kinzler,Kenneth W
AU  - Vogelstein,Bert
AU  - Velculescu,Victor E
TI  - Mutant PIK3CA promotes cell growth and invasion of human cancer cells
SN  - 1535-6108
PY  - 2005///0906
KW  - Amino Acid Substitution
KW  - Animals
KW  - Apoptosis
KW  - genetics
KW  - Apoptosis Regulatory Proteins
KW  - Base Sequence
KW  - Cell Line, Tumor
KW  - Cell Movement
KW  - Cell Proliferation
KW  - Chromones
KW  - pharmacology
KW  - Class I Phosphatidylinositol 3-Kinases
KW  - DNA-Binding Proteins
KW  - Enzyme Inhibitors
KW  - Forkhead Box Protein O1
KW  - Forkhead Box Protein O3
KW  - Forkhead Transcription Factors
KW  - Gene Targeting
KW  - Growth Substances
KW  - deficiency
KW  - Humans
KW  - Insulin
KW  - Membrane Glycoproteins
KW  - physiology
KW  - Mice
KW  - Mice, Nude
KW  - Morpholines
KW  - Mutation
KW  - Neoplasm Invasiveness
KW  - Neoplasms, Experimental
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Phosphorylation
KW  - drug effects
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-akt
KW  - Signal Transduction
KW  - TNF-Related Apoptosis-Inducing Ligand
KW  - Transcription Factors
KW  - Tumor Necrosis Factor-alpha
KW  - Xenograft Model Antitumor Assays
KW  - methods
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1016/j.ccr.2005.05.014
ER  -