Shushakova, Nelli <br/><br/>
Urokinase-induced activation of the gp130/Tyk2/Stat3 pathway mediates a pro-inflammatory effect in human mesangial cells via expression of the anaphylatoxin C5a receptor.  [electronic resource] 

 -  Journal of cell science  Jun 2005 
 - 2743-53 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9533 
<br/><br/><label>Standard No.: </label>10.1242/jcs.02409  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antigens, CD--metabolism<br/>Biological Transport<br/>Cytokine Receptor gp130<br/>DNA-Binding Proteins--metabolism<br/>Gene Expression Regulation--drug effects<br/>Glomerular Mesangium--drug effects<br/>Humans<br/>Inflammation Mediators--metabolism<br/>Lipopolysaccharides--pharmacology<br/>Membrane Glycoproteins--metabolism<br/>Membrane Proteins--genetics<br/>Mice<br/>Nephritis--chemically induced<br/>Protein-Tyrosine Kinases--genetics<br/>Receptor, Anaphylatoxin C5a--genetics<br/>Receptors, Complement--genetics<br/>STAT3 Transcription Factor<br/>Signal Transduction--drug effects<br/>TYK2 Kinase<br/>Trans-Activators--metabolism<br/>Up-Regulation--genetics<br/>Urokinase-Type Plasminogen Activator--pharmacology