TY - GEN AU - Kim,Seonil AU - Lapham,Andrea N AU - Freedman,Christopher G K AU - Reed,Tiffany L AU - Schmidt,Walter K TI - Yeast as a tractable genetic system for functional studies of the insulin-degrading enzyme SN - 0021-9258 PY - 2005///0922 KW - Alleles KW - Amino Acid Motifs KW - Amino Acid Sequence KW - Animals KW - Conserved Sequence KW - Electrophoresis, Polyacrylamide Gel KW - Fungal Proteins KW - genetics KW - Genetic Techniques KW - Genotype KW - Green Fluorescent Proteins KW - metabolism KW - Haploidy KW - Insulin KW - Insulysin KW - chemistry KW - Mass Spectrometry KW - Mating Factor KW - Metalloendopeptidases KW - Models, Genetic KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Mutation KW - Peptides KW - Plasmids KW - Point Mutation KW - Protein Binding KW - Protein Structure, Tertiary KW - Proteins KW - Rats KW - Saccharomyces cerevisiae Proteins KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization KW - Structure-Activity Relationship KW - Substrate Specificity KW - Time Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M414192200 ER -