TY - GEN AU - Hegde,Subray S AU - Vetting,Matthew W AU - Roderick,Steven L AU - Mitchenall,Lesley A AU - Maxwell,Anthony AU - Takiff,Howard E AU - Blanchard,John S TI - A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA SN - 1095-9203 PY - 2005///0616 KW - Amino Acid Sequence KW - Antitubercular Agents KW - chemistry KW - Bacterial Proteins KW - Ciprofloxacin KW - pharmacology KW - Crystallography, X-Ray KW - DNA Gyrase KW - metabolism KW - DNA, Bacterial KW - DNA, Superhelical KW - Drug Resistance, Bacterial KW - Drug Resistance, Microbial KW - physiology KW - Enzyme Inhibitors KW - Escherichia coli KW - enzymology KW - Fluoroquinolones KW - antagonists & inhibitors KW - Models, Molecular KW - Molecular Mimicry KW - Molecular Sequence Data KW - Monomeric GTP-Binding Proteins KW - Mycobacterium tuberculosis KW - drug effects KW - Protein Conformation KW - Protein Folding KW - Structure-Activity Relationship KW - Topoisomerase II Inhibitors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1126/science.1110699 ER -