Antonescu, Cristina R <br/><br/>
Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation.  [electronic resource] 

 -  Clinical cancer research : an official journal of the American Association for Cancer Research  Jun 2005 
 - 4182-90 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1078-0432 
<br/><br/><label>Standard No.: </label>10.1158/1078-0432.CCR-04-2245  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Amino Acid Sequence<br/>Antineoplastic Agents--pharmacology<br/>Benzamides<br/>Blotting, Western<br/>DNA Mutational Analysis<br/>Drug Resistance, Neoplasm--drug effects<br/>Female<br/>Gastrointestinal Stromal Tumors--drug therapy<br/>Genotype<br/>Humans<br/>Imatinib Mesylate<br/>Male<br/>Middle Aged<br/>Molecular Sequence Data<br/>Mutation<br/>Piperazines--pharmacology<br/>Protein-Tyrosine Kinases--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-kit--genetics<br/>Pyrimidines--pharmacology<br/>Receptor, Platelet-Derived Growth Factor alpha--genetics