TY - GEN AU - Wiens,Matthias AU - Korzhev,Michael AU - Krasko,Anatoli AU - Thakur,Narsinh L AU - Perović-Ottstadt,Sanja AU - Breter,Hans J AU - Ushijima,Hiroshi AU - Diehl-Seifert,Bärbel AU - Müller,Isabel M AU - Müller,Werner E G TI - Innate immune defense of the sponge Suberites domuncula against bacteria involves a MyD88-dependent signaling pathway. Induction of a perforin-like molecule SN - 0021-9258 PY - 2005///0922 KW - Adaptor Proteins, Signal Transducing KW - Amino Acid Sequence KW - Animals KW - Antigens, Differentiation KW - chemistry KW - Blotting, Northern KW - Blotting, Western KW - Cloning, Molecular KW - Cross-Linking Reagents KW - pharmacology KW - DNA, Complementary KW - metabolism KW - Dimerization KW - Fluorescein-5-isothiocyanate KW - Gene Library KW - Immunohistochemistry KW - Immunoprecipitation KW - In Situ Hybridization KW - Ligands KW - Lipopolysaccharides KW - Macrophages KW - Membrane Glycoproteins KW - Models, Biological KW - Molecular Sequence Data KW - Myeloid Differentiation Factor 88 KW - Perforin KW - Phylogeny KW - Pore Forming Cytotoxic Proteins KW - Protein Binding KW - Protein Structure, Tertiary KW - RNA KW - Receptors, Immunologic KW - Recombinant Proteins KW - Sequence Homology, Amino Acid KW - Signal Transduction KW - Suberites KW - immunology KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M504049200 ER -