TY  - GEN
AU  - Tarn,Chi
AU  - Merkel,Erin
AU  - Canutescu,Adrian A
AU  - Shen,Wei
AU  - Skorobogatko,Yuliya
AU  - Heslin,Martin J
AU  - Eisenberg,Burton
AU  - Birbe,Ruth
AU  - Patchefsky,Arthur
AU  - Dunbrack,Roland
AU  - Arnoletti,J Pablo
AU  - von Mehren,Margaret
AU  - Godwin,Andrew K
TI  - Analysis of KIT mutations in sporadic and familial gastrointestinal stromal tumors: therapeutic implications through protein modeling
SN  - 1078-0432
PY  - 2005///0823
KW  - Adult
KW  - Aged
KW  - Amino Acid Sequence
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Benzamides
KW  - Cell Transformation, Neoplastic
KW  - Crystallography, X-Ray
KW  - DNA Mutational Analysis
KW  - DNA, Neoplasm
KW  - analysis
KW  - Female
KW  - Gastrointestinal Stromal Tumors
KW  - genetics
KW  - Germ-Line Mutation
KW  - Humans
KW  - Imatinib Mesylate
KW  - Male
KW  - Middle Aged
KW  - Models, Chemical
KW  - Molecular Sequence Data
KW  - Pedigree
KW  - Piperazines
KW  - Platelet-Derived Growth Factor
KW  - biosynthesis
KW  - Protein Conformation
KW  - Proto-Oncogene Proteins c-kit
KW  - Pyrimidines
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1158/1078-0432.CCR-04-2515
ER  -