Analysis of KIT mutations in sporadic and familial gastrointestinal stromal tumors: therapeutic implications through protein modeling. [electronic resource]
- Clinical cancer research : an official journal of the American Association for Cancer Research May 2005
- 3668-77 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
1078-0432
10.1158/1078-0432.CCR-04-2515 doi
Adult Aged Amino Acid Sequence Antineoplastic Agents--pharmacology Benzamides Cell Transformation, Neoplastic Crystallography, X-Ray DNA Mutational Analysis DNA, Neoplasm--analysis Female Gastrointestinal Stromal Tumors--genetics Germ-Line Mutation Humans Imatinib Mesylate Male Middle Aged Models, Chemical Molecular Sequence Data Pedigree Piperazines--pharmacology Platelet-Derived Growth Factor--biosynthesis Protein Conformation Proto-Oncogene Proteins c-kit--biosynthesis Pyrimidines--pharmacology