Tarn, Chi

Analysis of KIT mutations in sporadic and familial gastrointestinal stromal tumors: therapeutic implications through protein modeling. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research May 2005 - 3668-77 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1078-0432

10.1158/1078-0432.CCR-04-2515 doi


Adult
Aged
Amino Acid Sequence
Antineoplastic Agents--pharmacology
Benzamides
Cell Transformation, Neoplastic
Crystallography, X-Ray
DNA Mutational Analysis
DNA, Neoplasm--analysis
Female
Gastrointestinal Stromal Tumors--genetics
Germ-Line Mutation
Humans
Imatinib Mesylate
Male
Middle Aged
Models, Chemical
Molecular Sequence Data
Pedigree
Piperazines--pharmacology
Platelet-Derived Growth Factor--biosynthesis
Protein Conformation
Proto-Oncogene Proteins c-kit--biosynthesis
Pyrimidines--pharmacology