Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death. [electronic resource]
- Molecular cancer therapeutics May 2005
- 733-42 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
1535-7163
10.1158/1535-7163.MCT-04-0301 doi
Antimetabolites, Antineoplastic--pharmacology Antineoplastic Agents--pharmacology Antineoplastic Agents, Phytogenic--pharmacology Apoptosis--drug effects Caspase 3 Caspases--metabolism Cathepsin D--antagonists & inhibitors Cisplatin--pharmacology Cytochromes c--drug effects Cytosol--metabolism Enzyme Activation--drug effects Etoposide--pharmacology Fluorouracil--pharmacology HeLa Cells Humans Protein Transport RNA, Small Interfering--pharmacology U937 Cells