TY  - GEN
AU  - Plescia,Janet
AU  - Salz,Whitney
AU  - Xia,Fang
AU  - Pennati,Marzia
AU  - Zaffaroni,Nadia
AU  - Daidone,Maria Grazia
AU  - Meli,Massimiliano
AU  - Dohi,Takehiko
AU  - Fortugno,Paola
AU  - Nefedova,Yulia
AU  - Gabrilovich,Dmitry I
AU  - Colombo,Giorgio
AU  - Altieri,Dario C
TI  - Rational design of shepherdin, a novel anticancer agent
SN  - 1535-6108
PY  - 2005///0826
KW  - Adenosine Triphosphate
KW  - metabolism
KW  - Animals
KW  - Antennapedia Homeodomain Protein
KW  - Antimetabolites, Antineoplastic
KW  - chemistry
KW  - Apoptosis
KW  - drug effects
KW  - Benzoquinones
KW  - Binding Sites
KW  - genetics
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Cytochromes c
KW  - Drug Design
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Female
KW  - Fibroblasts
KW  - Gene Products, tat
KW  - HSP90 Heat-Shock Proteins
KW  - HeLa Cells
KW  - Homeodomain Proteins
KW  - Humans
KW  - Inhibitor of Apoptosis Proteins
KW  - Lactams, Macrocyclic
KW  - Male
KW  - Mice
KW  - Mice, SCID
KW  - Microtubule-Associated Proteins
KW  - Models, Molecular
KW  - Molecular Mimicry
KW  - Neoplasm Proteins
KW  - Nuclear Proteins
KW  - Peptide Fragments
KW  - Prostatic Neoplasms
KW  - Protein Binding
KW  - Protein Conformation
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Rifabutin
KW  - analogs & derivatives
KW  - Stem Cells
KW  - Survivin
KW  - Telomerase
KW  - Transcription Factors
KW  - Tumor Suppressor Protein p53
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1016/j.ccr.2005.03.035
ER  -