A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing. [electronic resource]
- The Journal of biological chemistry Aug 2005
- 29067-72 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M500002200 doi
Allosteric Site Amino Acids--chemistry Aminoacylation Blotting, Western Calcium--metabolism Cell Line Cytoplasm--metabolism DNA Mutational Analysis Humans Kinetics Mutagenesis, Site-Directed Mutation Phenylalanine--chemistry Protein Binding Protein Structure, Tertiary Receptors, Calcium-Sensing--chemistry Sensitivity and Specificity Time Factors Transfection