Wang, G

Antitumor effect of beta-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death. [electronic resource] - Cellular and molecular life sciences : CMLS Apr 2005 - 881-93 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1420-682X

10.1007/s00018-005-5017-3 doi


Apoptosis--drug effects
CDC2 Protein Kinase--metabolism
Carcinoma, Non-Small-Cell Lung--drug therapy
Caspases--metabolism
Cell Cycle--drug effects
Cell Cycle Proteins--metabolism
Cell Proliferation--drug effects
Cells, Cultured
Checkpoint Kinase 2
Cyclin-Dependent Kinase Inhibitor p27
Cytochromes c--metabolism
Enzyme Activation--drug effects
Gene Expression Regulation, Neoplastic--drug effects
Genes, bcl-2--physiology
Humans
Lung Neoplasms--drug therapy
Phosphorylation--drug effects
Poly(ADP-ribose) Polymerases--physiology
Protein Serine-Threonine Kinases--metabolism
Sesquiterpenes--pharmacology
Tumor Suppressor Proteins--metabolism
cdc25 Phosphatases--metabolism