Richardson, Terrilyn A

Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice. [electronic resource] - The Journal of pharmacology and experimental therapeutics Aug 2005 - 703-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

0022-3565

10.1124/jpet.105.085456 doi


Acute-Phase Proteins--biosynthesis
Animals
Blotting, Western
Cytochrome P-450 Enzyme System--biosynthesis
Cytokines--biosynthesis
DNA, Complementary--biosynthesis
Down-Regulation--drug effects
Endotoxins--toxicity
Female
Gene Expression Regulation, Enzymologic--drug effects
Inflammation--chemically induced
Lipopolysaccharides--pharmacology
Liver--drug effects
Mice
Mice, Knockout
Microsomes, Liver--drug effects
PPAR alpha--drug effects
Pregnane X Receptor
RNA--biosynthesis
Receptors, Cytoplasmic and Nuclear--drug effects
Receptors, Steroid--drug effects
Reverse Transcriptase Polymerase Chain Reaction