TY - GEN AU - Long,Xiaomeng AU - Lin,Yenshou AU - Ortiz-Vega,Sara AU - Yonezawa,Kazuyoshi AU - Avruch,Joseph TI - Rheb binds and regulates the mTOR kinase SN - 0960-9822 PY - 2005///0815 KW - Adaptor Proteins, Signal Transducing KW - Cells, Cultured KW - DNA Primers KW - Enzyme Activation KW - physiology KW - Guanosine Triphosphate KW - metabolism KW - Humans KW - Immunoblotting KW - Monomeric GTP-Binding Proteins KW - genetics KW - Mutation KW - Neuropeptides KW - Phosphorylation KW - Plasmids KW - Protein Biosynthesis KW - Protein Kinases KW - Proteins KW - RNA, Messenger KW - Ras Homolog Enriched in Brain Protein KW - Regulatory-Associated Protein of mTOR KW - Repressor Proteins KW - Ribosomal Protein S6 Kinases, 70-kDa KW - Signal Transduction KW - TOR Serine-Threonine Kinases KW - Transfection KW - Tuberous Sclerosis Complex 2 Protein KW - Tumor Suppressor Proteins N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/j.cub.2005.02.053 ER -