Honore, Prisca <br/><br/>
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Jul 2005 
 - 410-21 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-3565 
<br/><br/><label>Standard No.: </label>10.1124/jpet.105.083915  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acute Disease<br/>Analgesics<br/>Animals<br/>Capsaicin<br/>Carrageenan<br/>Chronic Disease<br/>Dose-Response Relationship, Drug<br/>Edema--chemically induced<br/>Formaldehyde<br/>Freund's Adjuvant<br/>Hot Temperature<br/>Hyperalgesia--chemically induced<br/>Inflammation--complications<br/>Isoquinolines--pharmacology<br/>Ligation<br/>Male<br/>Motor Activity--drug effects<br/>Osteoarthritis--complications<br/>Pain--drug therapy<br/>Pain Measurement--drug effects<br/>Pain, Postoperative--drug therapy<br/>Postural Balance--drug effects<br/>Rats<br/>Rats, Sprague-Dawley<br/>Receptors, Drug--antagonists & inhibitors<br/>Sciatic Nerve--pathology<br/>Spinal Nerves--pathology<br/>Urea--analogs & derivatives