Duan, Jianming

Irreversible cellular senescence induced by prolonged exposure to H2O2 involves DNA-damage-and-repair genes and telomere shortening. [electronic resource] - The international journal of biochemistry & cell biology Jul 2005 - 1407-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1357-2725

10.1016/j.biocel.2005.01.010 doi


Cell Cycle Proteins--biosynthesis
Cell Proliferation--drug effects
Cells, Cultured
Cellular Senescence--drug effects
Comet Assay
Cyclin-Dependent Kinase Inhibitor p21
DNA Damage--genetics
DNA Repair--genetics
Diploidy
Electrophoretic Mobility Shift Assay
Fibroblasts--drug effects
Humans
Hydrogen Peroxide--pharmacology
Intracellular Signaling Peptides and Proteins--metabolism
Oxidative Stress
Telomere--drug effects
Time Factors
Tumor Suppressor Protein p53--biosynthesis
beta-Galactosidase--metabolism
GADD45 Proteins