TY  - GEN
AU  - Schwarz,Jacob B
AU  - Gibbons,Sian E
AU  - Graham,Shelley R
AU  - Colbry,Norman L
AU  - Guzzo,Peter R
AU  - Le,Van-Duc
AU  - Vartanian,Mark G
AU  - Kinsora,Jack J
AU  - Lotarski,Susan M
AU  - Li,Zheng
AU  - Dickerson,Melvin R
AU  - Su,Ti-Zhi
AU  - Weber,Mark L
AU  - El-Kattan,Ayman
AU  - Thorpe,Andrew J
AU  - Donevan,Sean D
AU  - Taylor,Charles P
AU  - Wustrow,David J
TI  - Novel cyclopropyl beta-amino acid analogues of pregabalin and gabapentin that target the alpha2-delta protein
SN  - 0022-2623
PY  - 2005///0524
KW  - Administration, Oral
KW  - Amines
KW  - chemical synthesis
KW  - Amino Acid Transport System L
KW  - metabolism
KW  - Amino Acids
KW  - chemistry
KW  - Animals
KW  - Anticonvulsants
KW  - Biological Transport, Active
KW  - Blood-Brain Barrier
KW  - CHO Cells
KW  - Calcium Channels
KW  - drug effects
KW  - Cricetinae
KW  - Cricetulus
KW  - Cyclization
KW  - Cyclohexanecarboxylic Acids
KW  - Cyclopropanes
KW  - Gabapentin
KW  - In Vitro Techniques
KW  - Injections, Intraventricular
KW  - Ion Channel Gating
KW  - Male
KW  - Mice
KW  - Mice, Inbred DBA
KW  - Nitriles
KW  - Pregabalin
KW  - Protein Subunits
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Swine
KW  - gamma-Aminobutyric Acid
KW  - analogs & derivatives
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm0491086
ER  -