Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation. [electronic resource]
- Molecular cancer therapeutics Apr 2005
- 529-36 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
1535-7163
10.1158/1535-7163.MCT-04-0130 doi
Animals Antigens, Nuclear--genetics Antineoplastic Agents, Phytogenic--pharmacology Apoptosis Blotting, Western Cell Line, Tumor Cricetinae DNA Damage DNA Repair DNA-Binding Proteins--genetics Dimerization Dose-Response Relationship, Radiation Etoposide--pharmacology Gamma Rays HeLa Cells Humans Ku Autoantigen Microscopy, Fluorescence Neoplasms--therapy Phenotype RNA, Messenger--metabolism RNA, Small Interfering--genetics Telomere--ultrastructure Time Factors Topoisomerase II Inhibitors Transfection VDJ Recombinases--metabolism