DNA damage uncouples the mitogenic response to IGF-I in MCF-7 malignant breast cancer cells by switching the roles of PI3 kinase and p21WAF1/Cip1. [electronic resource]
- International journal of cancer Sep 2005
- 506-13 p. digital
Publication Type: Journal Article
0020-7136
10.1002/ijc.21029 doi
Breast Neoplasms--genetics Cell Cycle Cell Cycle Proteins--biosynthesis Cyclin-Dependent Kinase Inhibitor p21 DNA Damage DNA Repair Female Humans Insulin-Like Growth Factor I--physiology Mitogens Phosphatidylinositol 3-Kinases--biosynthesis Signal Transduction Tumor Cells, Cultured Tumor Suppressor Protein p53--physiology