Kim, Su-Jin <br/><br/>
Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.  [electronic resource] 

 -  The Journal of biological chemistry  Jun 2005 
 - 22297-307 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M500540200  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis<br/>Blotting, Western<br/>Cell Line<br/>Cell Survival<br/>Dose-Response Relationship, Drug<br/>Down-Regulation<br/>Forkhead Box Protein O1<br/>Forkhead Transcription Factors<br/>Gastric Inhibitory Polypeptide--chemistry<br/>Humans<br/>Immunohistochemistry<br/>Islets of Langerhans--cytology<br/>Luciferases--metabolism<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Mice, Transgenic<br/>Microscopy, Confocal<br/>Microscopy, Fluorescence<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Phosphorylation<br/>Promoter Regions, Genetic<br/>Protein Serine-Threonine Kinases--metabolism<br/>Proto-Oncogene Proteins--metabolism<br/>Proto-Oncogene Proteins c-akt<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Rats<br/>Rats, Zucker<br/>Signal Transduction<br/>Subcellular Fractions<br/>Time Factors<br/>Transcription Factors--metabolism<br/>Transcription, Genetic<br/>bcl-2-Associated X Protein