TY - GEN AU - Ishibe,Tatsuya AU - Nakayama,Tomitaka AU - Okamoto,Takeshi AU - Aoyama,Tomoki AU - Nishijo,Koichi AU - Shibata,Kotaro Roberts AU - Shima,Yasuko AU - Nagayama,Satoshi AU - Katagiri,Toyomasa AU - Nakamura,Yusuke AU - Nakamura,Takashi AU - Toguchida,Junya TI - Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy SN - 1078-0432 PY - 2005///0808 KW - Animals KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Dose-Response Relationship, Drug KW - Enzyme Activation KW - Female KW - Fibroblast Growth Factors KW - genetics KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - Mitogen-Activated Protein Kinase 1 KW - metabolism KW - Mitogen-Activated Protein Kinase 3 KW - Mitogen-Activated Protein Kinases KW - Phosphorylation KW - Protein Isoforms KW - Pyrimidines KW - pharmacology KW - Pyrroles KW - RNA, Messenger KW - Receptors, Fibroblast Growth Factor KW - antagonists & inhibitors KW - Recombinant Proteins KW - Reverse Transcriptase Polymerase Chain Reaction KW - Sarcoma, Synovial KW - Signal Transduction KW - Urea KW - analogs & derivatives KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-04-2057 ER -