TY - GEN AU - Mittal,Sachin AU - Song,Xueqin AU - Vig,Balvinder S AU - Landowski,Christopher P AU - Kim,Insook AU - Hilfinger,John M AU - Amidon,Gordon L TI - Prolidase, a potential enzyme target for melanoma: design of proline-containing dipeptide-like prodrugs SN - 1543-8384 PY - 2005///0512 KW - Amino Acid Sequence KW - Antineoplastic Agents KW - Caco-2 Cells KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Colorimetry KW - Dipeptidases KW - therapeutic use KW - Drug Design KW - Feasibility Studies KW - Humans KW - K562 Cells KW - Melanoma KW - drug therapy KW - Melphalan KW - analogs & derivatives KW - Oligonucleotide Array Sequence Analysis KW - Prodrugs KW - chemical synthesis KW - Proline KW - Reverse Transcriptase Polymerase Chain Reaction KW - Substrate Specificity N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/mp049922p ER -