TY - GEN AU - Hamill,Terence G AU - Krause,Stephen AU - Ryan,Christine AU - Bonnefous,Celine AU - Govek,Steve AU - Seiders,T Jon AU - Cosford,Nicholas D P AU - Roppe,Jeffrey AU - Kamenecka,Ted AU - Patel,Shil AU - Gibson,Raymond E AU - Sanabria,Sandra AU - Riffel,Kerry AU - Eng,Waisi AU - King,Christopher AU - Yang,Xiaoqing AU - Green,Mitchell D AU - O'Malley,Stacey S AU - Hargreaves,Richard AU - Burns,H Donald TI - Synthesis, characterization, and first successful monkey imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) PET radiotracers SN - 0887-4476 PY - 2005///0729 KW - Animals KW - Autoradiography KW - methods KW - Binding Sites KW - drug effects KW - Brain KW - anatomy & histology KW - Brain Chemistry KW - Brain Mapping KW - Carbon Radioisotopes KW - pharmacokinetics KW - Dose-Response Relationship, Drug KW - Excitatory Amino Acid Antagonists KW - chemical synthesis KW - Fluorine Radioisotopes KW - Humans KW - In Vitro Techniques KW - Macaca mulatta KW - Magnetic Resonance Imaging KW - Microsomes, Liver KW - Positron-Emission Tomography KW - Rats KW - Receptor, Metabotropic Glutamate 5 KW - Receptors, Metabotropic Glutamate KW - antagonists & inhibitors KW - Statistics as Topic KW - Time Factors N1 - Publication Type: Comparative Study; Journal Article UR - https://doi.org/10.1002/syn.20147 ER -