TY - GEN AU - Groeneveld,Geert Jan AU - van der Tweel,Ingeborg AU - Wokke,John H J AU - van den Berg,Leonard H TI - Sequential designs for clinical trials in amyotrophic lateral sclerosis SN - 1466-0822 PY - 2005///0512 KW - Amyotrophic Lateral Sclerosis KW - drug therapy KW - Confidence Intervals KW - Creatine KW - therapeutic use KW - Double-Blind Method KW - Humans KW - Randomized Controlled Trials as Topic KW - methods KW - Research Design KW - Sample Size KW - Survival Analysis N1 - Publication Type: Comparative Study; Journal Article ER -