TY  - GEN
AU  - Beuvink,Iwan
AU  - Boulay,Anne
AU  - Fumagalli,Stefano
AU  - Zilbermann,Frederic
AU  - Ruetz,Stephan
AU  - O'Reilly,Terence
AU  - Natt,Francois
AU  - Hall,Jonathan
AU  - Lane,Heidi A
AU  - Thomas,George
TI  - The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation
SN  - 0092-8674
PY  - 2005///0516
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Cell Cycle Proteins
KW  - antagonists & inhibitors
KW  - Cell Survival
KW  - Cisplatin
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - DNA Damage
KW  - Drug Synergism
KW  - Everolimus
KW  - Humans
KW  - Mutation
KW  - Polyribosomes
KW  - Protein Biosynthesis
KW  - Protein Kinases
KW  - genetics
KW  - RNA, Small Interfering
KW  - Sirolimus
KW  - analogs & derivatives
KW  - TOR Serine-Threonine Kinases
KW  - Tumor Cells, Cultured
KW  - Tumor Suppressor Protein p53
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.cell.2004.12.040
ER  -