Merl, Sabine

Targeting 2A protease by RNA interference attenuates coxsackieviral cytopathogenicity and promotes survival in highly susceptible mice. [electronic resource] - Circulation Apr 2005 - 1583-92 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4539

10.1161/01.CIR.0000160360.02040.AB doi


Animals
Cell Survival--drug effects
Coxsackievirus Infections--drug therapy
Cysteine Endopeptidases--genetics
Drug Delivery Systems
Enterovirus--enzymology
Gene Expression Regulation, Viral--drug effects
HeLa Cells
Humans
Mice
Mice, Knockout
RNA Interference
RNA, Small Interfering--pharmacology
Receptors, Interferon--deficiency
Survival Rate
Transfection
Treatment Outcome
Viral Proteins--antagonists & inhibitors
Virulence
Virus Replication--drug effects